Search results for "Laser illumination"
showing 4 items of 4 documents
Express RGB mapping of three to five skin chromophores
2017
Skin melanin, oxy- and deoxy-hemoglobin were snapshot-mapped under simultaneous 448-532-659 nm laser illumination by a smartphone RGB camera. Experimental prototypes for double-snapshot RGB mapping of four (melanin, bilirubin, oxy- and deoxy-hemoglobin) and five (melanin, bilirubin, lipids, oxy- and deoxy-hemoglobin) skin chromophores with reduced laser speckle artefacts have been developed and tested. A set of 405-448-532-659 nm lasers were used for four chromophores mapping, and a set of 405-448-532-659-842 nm lasers for five chromophores mapping. Clinical tests confirmed functionality of the developed devices.
Smartphone snapshot mapping of skin chromophores under triple-wavelength laser illumination
2017
Abstract Chromophore distribution maps are useful tools for skin malformation severity assessment and for monitoring of skin recovery after burns, surgeries, and other interactions. The chromophore maps can be obtained by processing several spectral images of skin, e.g., captured by hyperspectral or multispectral cameras during seconds or even minutes. To avoid motion artifacts and simplify the procedure, a single-snapshot technique for mapping melanin, oxyhemoglobin, and deoxyhemoglobin of in-vivo skin by a smartphone under simultaneous three-wavelength (448–532–659 nm) laser illumination is proposed and examined. Three monochromatic spectral images related to the illumination wavelengths …
The efficacy of photodynamic therapy in rat tongue dysplasia
2017
Background Photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) has previously shown promising results in cancerous cell destruction. The present study was conducted to evaluate the efficacy of this treatment option on oral epithelial dysplasia in Wistar rats. Furthermore, microscopic effects of systemic versus topical administration of ALA before laser illumination was assessed. Material and Methods Thirty male Wistar rats (200- 250 grams) were used in the present study. Tongue dysplasia was induced by a daily delivery of a 20 ppm solution of 4-nitroquinoline -1- oxide (4NQO) for 3 months. Then, rats were divided into 3 groups of 10 including, group 1 that was received systemic ALA…
Skin haemoglobin mapping: comparison of multi-spectral imaging and selective R-G-B analysis
2010
The multi-spectral imaging technique has been used for distant mapping of in-vivo skin haemoglobin. Besides, potential of selective R-G-B analysis of skin images has been studied under bi-chromatic (532 nm and 635 nm) laser illumination.